How severe is CVE-2021-25252?

CVE-2021-25252 has a CVSS 3.x base score of 5.5, rated medium severity. It is exploitable over local access with low attack complexity, requires low privileges and no user interaction. Impact on confidentiality is none, integrity none, and availability high.

Is CVE-2021-25252 being actively exploited?

It is not currently listed in CISA's KEV catalog. Its EPSS exploit-prediction score is 1% (42nd percentile), an estimate of the probability of exploitation in the next 30 days.

What products are affected by CVE-2021-25252?

CVE-2021-25252 primarily affects Trendmicro Apex Central. In total, 23 product configurations (CPEs) are listed as vulnerable; see the affected-products list for the exact versions.

How do I fix CVE-2021-25252?

Review the linked vendor and NVD advisories for patched versions and mitigations, then upgrade or apply the recommended workaround.

When was CVE-2021-25252 published?

CVE-2021-25252 was published on 2021-03-03 and last updated on 2026-06-17.

CVE-2021-25252

CVE-2021-25252 is a medium-severity vulnerability in Trendmicro Apex Central with a CVSS 3.x base score of 5.5. It is not currently listed as actively exploited by CISA, and its EPSS exploit-prediction score is low. The underlying weakness is classified as CWE-400.

Key facts

Severity: Medium (CVSS 3.x base score 5.5)
CVSS v2: 4.9
EPSS exploit prediction: 1% (42nd percentile)
Actively exploited: Not listed in CISA KEV
Weakness: CWE-400
Affected product: Trendmicro Apex Central
Published: 2021-03-03
Last modified: 2026-06-17

Description

Trend Micro's Virus Scan API (VSAPI) and Advanced Threat Scan Engine (ATSE) - are vulnerable to a memory exhaustion vulnerability that may lead to denial-of-service or system freeze if exploited by an attacker using a specially crafted file.

Frequently asked questions

What is CVE-2021-25252?: Trend Micro's Virus Scan API (VSAPI) and Advanced Threat Scan Engine (ATSE) - are vulnerable to a memory exhaustion vulnerability that may lead to denial-of-service or system freeze if exploited by an attacker using a specially crafted file.
How severe is CVE-2021-25252?: CVE-2021-25252 has a CVSS 3.x base score of 5.5, rated medium severity. It is exploitable over local access with low attack complexity, requires low privileges and no user interaction. Impact on confidentiality is none, integrity none, and availability high.
Is CVE-2021-25252 being actively exploited?: It is not currently listed in CISA's KEV catalog. Its EPSS exploit-prediction score is 1% (42nd percentile), an estimate of the probability of exploitation in the next 30 days.
What products are affected by CVE-2021-25252?: CVE-2021-25252 primarily affects Trendmicro Apex Central. In total, 23 product configurations (CPEs) are listed as vulnerable; see the affected-products list for the exact versions.
How do I fix CVE-2021-25252?: Review the linked vendor and NVD advisories for patched versions and mitigations, then upgrade or apply the recommended workaround.
When was CVE-2021-25252 published?: CVE-2021-25252 was published on 2021-03-03 and last updated on 2026-06-17.

References

https://success.trendmicro.com/solution/000285675

Affected products (23)

cpe:2.3:a:trendmicro:apex_central:2019:-:*:*:*:*:*:*
cpe:2.3:a:trendmicro:apex_one:2019:-:*:*:*:*:*:*
cpe:2.3:a:trendmicro:cloud_edge:5.0:*:*:*:*:*:*:*
cpe:2.3:a:trendmicro:apex_one:-:-:*:*:*:*:*:*
cpe:2.3:a:trendmicro:deep_security:10.0:-:*:*:*:*:*:*
cpe:2.3:a:trendmicro:deep_security:11.0:-:*:*:*:*:*:*
cpe:2.3:a:trendmicro:deep_security:12.0:-:*:*:*:*:*:*
cpe:2.3:a:trendmicro:deep_security:20.0:-:*:*:long_term_support:*:*:*
cpe:2.3:a:trendmicro:control_manager:7.0:-:*:*:*:*:*:*
cpe:2.3:a:trendmicro:deep_discovery_analyzer:5.1:-:*:*:*:*:*:*
cpe:2.3:a:trendmicro:deep_discovery_email_inspector:2.5:-:*:*:*:*:*:*
cpe:2.3:a:trendmicro:deep_discovery_inspector:3.8:-:*:*:*:*:*:*
cpe:2.3:a:trendmicro:interscan_messaging_security_virtual_appliance:9.1:-:*:*:*:*:*:*
cpe:2.3:a:trendmicro:interscan_web_security_virtual_appliance:6.5:-:*:*:*:*:*:*
cpe:2.3:a:trendmicro:officescan:-:*:*:*:*:*:*:*
cpe:2.3:a:trendmicro:portal_protect:2.6:*:*:*:*:*:*:*
cpe:2.3:a:trendmicro:scanmail:14.0:*:*:*:*:microsoft_exchange:*:*
cpe:2.3:a:trendmicro:scanmail_for_ibm_domino:5.8:-:*:*:*:*:*:*
cpe:2.3:a:trendmicro:serverprotect_for_storage:6.0:-:*:*:*:*:*:*
cpe:2.3:a:trendmicro:serverprotect:5.8:-:*:*:*:*:*:*
cpe:2.3:a:trendmicro:serverprotect_for_network_appliance_filers:5.8:-:*:*:*:*:*:*
cpe:2.3:a:trendmicro:safe_lock:1.1:-:*:*:txone:*:*:*
cpe:2.3:a:trendmicro:worry-free_business_security:10.1:-:*:*:*:*:*:*

More vulnerabilities in Trendmicro Apex Central

CVE-2025-69258 — Critical (CVSS 9.8): A LoadLibraryEX vulnerability in Trend Micro Apex Central could allow an unauthenticated remote attacker to load an…
CVE-2025-49220 — Critical (CVSS 9.8): An insecure deserialization operation in Trend Micro Apex Central below version 8.0.7007 could lead to a…
CVE-2025-49219 — Critical (CVSS 9.8): An insecure deserialization operation in Trend Micro Apex Central below versions 8.0.7007 could lead to a…
CVE-2022-26871 — Critical (CVSS 9.8): An arbitrary file upload vulnerability in Trend Micro Apex Central could allow an unauthenticated remote attacker to…
CVE-2023-52324 — High (CVSS 8.8): An unrestricted file upload vulnerability in Trend Micro Apex Central could allow a remote attacker to create arbitrary…
CVE-2023-32530 — High (CVSS 8.8): Vulnerable modules of Trend Micro Apex Central (on-premise) contain vulnerabilities which would allow authenticated…

All CVEs affecting Trendmicro Apex Central →

Other CWE-400 (Uncontrolled Resource Consumption) vulnerabilities

CVE-2026-46775 — Critical (CVSS 9.9): Vulnerability in Oracle REST Data Services (component: Core). Supported versions that are affected are 24.2.0-26.1.0.…
CVE-2025-61303 — Critical (CVSS 9.8): Hatching Triage Sandbox Windows 10 build 2004 (2025-08-14) and Windows 10 LTSC 2021(2025-08-14) contains a…
CVE-2025-43193 — Critical (CVSS 9.8): The issue was addressed with improved memory handling. This issue is fixed in macOS Sequoia 15.6, macOS Sonoma 14.7.7,…
CVE-2025-24269 — Critical (CVSS 9.8): The issue was addressed with improved memory handling. This issue is fixed in macOS Sequoia 15.4. An app may be able to…
CVE-2025-24264 — Critical (CVSS 9.8): The issue was addressed with improved memory handling. This issue is fixed in Safari 18.4, iOS 18.4 and iPadOS 18.4,…
CVE-2025-24260 — Critical (CVSS 9.8): The issue was addressed with improved memory handling. This issue is fixed in macOS Sequoia 15.4, macOS Sonoma 14.7.5,…

Browse all CWE-400 (Uncontrolled Resource Consumption) vulnerabilities →