How severe is CVE-2022-1517?

CVE-2022-1517 has a CVSS 3.x base score of 10.0, rated critical severity. It is exploitable over network with low attack complexity, requires no privileges and no user interaction. Impact on confidentiality is high, integrity high, and availability high.

Is CVE-2022-1517 being actively exploited?

It is not currently listed in CISA's KEV catalog. Its EPSS exploit-prediction score is 2% (73rd percentile), an estimate of the probability of exploitation in the next 30 days.

What products are affected by CVE-2022-1517?

CVE-2022-1517 affects Illumina Local Run Manager. See the affected-products list for the exact vulnerable versions.

How do I fix CVE-2022-1517?

Review the linked vendor and NVD advisories for patched versions and mitigations, then upgrade or apply the recommended workaround. Given its critical severity, prioritise patching exposed systems.

When was CVE-2022-1517 published?

CVE-2022-1517 was published on 2022-06-24 and last updated on 2026-06-17.

CVE-2022-1517

CVE-2022-1517 is a critical-severity vulnerability in Illumina Local Run Manager with a CVSS 3.x base score of 10.0. It is not currently listed as actively exploited by CISA, and its EPSS exploit-prediction score is low. The underlying weakness is classified as CWE-269.

Key facts

Severity: Critical (CVSS 3.x base score 10.0)
CVSS v2: 10.0
EPSS exploit prediction: 2% (73rd percentile)
Actively exploited: Not listed in CISA KEV
Weakness: CWE-269
Affected product: Illumina Local Run Manager
Published: 2022-06-24
Last modified: 2026-06-17

Description

LRM utilizes elevated privileges. An unauthenticated malicious actor can upload and execute code remotely at the operating system level, which can allow an attacker to change settings, configurations, software, or access sensitive data on the affected produc. An attacker could also exploit this vulnerability to access APIs not intended for general use and interact through the network.

Frequently asked questions

What is CVE-2022-1517?: LRM utilizes elevated privileges. An unauthenticated malicious actor can upload and execute code remotely at the operating system level, which can allow an attacker to change settings, configurations, software, or access sensitive data on the affected produc. An attacker could also exploit this vulnerability to access APIs not intended for general use and interact through the network.
How severe is CVE-2022-1517?: CVE-2022-1517 has a CVSS 3.x base score of 10.0, rated critical severity. It is exploitable over network with low attack complexity, requires no privileges and no user interaction. Impact on confidentiality is high, integrity high, and availability high.
Is CVE-2022-1517 being actively exploited?: It is not currently listed in CISA's KEV catalog. Its EPSS exploit-prediction score is 2% (73rd percentile), an estimate of the probability of exploitation in the next 30 days.
What products are affected by CVE-2022-1517?: CVE-2022-1517 affects Illumina Local Run Manager. See the affected-products list for the exact vulnerable versions.
How do I fix CVE-2022-1517?: Review the linked vendor and NVD advisories for patched versions and mitigations, then upgrade or apply the recommended workaround. Given its critical severity, prioritise patching exposed systems.
When was CVE-2022-1517 published?: CVE-2022-1517 was published on 2022-06-24 and last updated on 2026-06-17.

References

https://www.cisa.gov/uscert/ics/advisories/icsa-22-153-02

Affected products (1)

cpe:2.3:a:illumina:local_run_manager:*:*:*:*:*:*:*:*

More vulnerabilities in Illumina Local Run Manager

CVE-2022-1519 — Critical (CVSS 10.0): LRM does not restrict the types of files that can be uploaded to the affected product. A malicious actor can upload any…
CVE-2022-1518 — Critical (CVSS 10.0): LRM contains a directory traversal vulnerability that can allow a malicious actor to upload outside the intended…
CVE-2022-1521 — Critical (CVSS 9.1): LRM does not implement authentication or authorization by default. A malicious actor can inject, replay, modify, and/or…
CVE-2022-1524 — High (CVSS 7.4): LRM version 2.4 and lower does not implement TLS encryption. A malicious actor can MITM attack sensitive data…

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