How severe is CVE-2022-46280?

CVE-2022-46280 has a CVSS 3.x base score of 9.8, rated critical severity. It is exploitable over network with low attack complexity, requires no privileges and no user interaction. Impact on confidentiality is high, integrity high, and availability high.

Is CVE-2022-46280 being actively exploited?

It is not currently listed in CISA's KEV catalog. Its EPSS exploit-prediction score is 1% (54th percentile), an estimate of the probability of exploitation in the next 30 days.

What products are affected by CVE-2022-46280?

CVE-2022-46280 affects Openbabel Open Babel. See the affected-products list for the exact vulnerable versions.

How do I fix CVE-2022-46280?

Review the linked vendor and NVD advisories for patched versions and mitigations, then upgrade or apply the recommended workaround. Given its critical severity, prioritise patching exposed systems.

When was CVE-2022-46280 published?

CVE-2022-46280 was published on 2023-07-21 and last updated on 2026-06-17.

CVE-2022-46280

CVE-2022-46280 is a critical-severity vulnerability in Openbabel Open Babel with a CVSS 3.x base score of 9.8. It is not currently listed as actively exploited by CISA, and its EPSS exploit-prediction score is low. The underlying weakness is classified as CWE-824.

Key facts

Severity: Critical (CVSS 3.x base score 9.8)
EPSS exploit prediction: 1% (54th percentile)
Actively exploited: Not listed in CISA KEV
Weakness: CWE-824
Affected product: Openbabel Open Babel
Published: 2023-07-21
Last modified: 2026-06-17

Description

A use of uninitialized pointer vulnerability exists in the PQS format pFormat functionality of Open Babel 3.1.1 and master commit 530dbfa3. A specially crafted malformed file can lead to arbitrary code execution. An attacker can provide a malicious file to trigger this vulnerability.

Frequently asked questions

What is CVE-2022-46280?: A use of uninitialized pointer vulnerability exists in the PQS format pFormat functionality of Open Babel 3.1.1 and master commit 530dbfa3. A specially crafted malformed file can lead to arbitrary code execution. An attacker can provide a malicious file to trigger this vulnerability.
How severe is CVE-2022-46280?: CVE-2022-46280 has a CVSS 3.x base score of 9.8, rated critical severity. It is exploitable over network with low attack complexity, requires no privileges and no user interaction. Impact on confidentiality is high, integrity high, and availability high.
Is CVE-2022-46280 being actively exploited?: It is not currently listed in CISA's KEV catalog. Its EPSS exploit-prediction score is 1% (54th percentile), an estimate of the probability of exploitation in the next 30 days.
What products are affected by CVE-2022-46280?: CVE-2022-46280 affects Openbabel Open Babel. See the affected-products list for the exact vulnerable versions.
How do I fix CVE-2022-46280?: Review the linked vendor and NVD advisories for patched versions and mitigations, then upgrade or apply the recommended workaround. Given its critical severity, prioritise patching exposed systems.
When was CVE-2022-46280 published?: CVE-2022-46280 was published on 2023-07-21 and last updated on 2026-06-17.

References

Affected products (1)

cpe:2.3:a:openbabel:open_babel:3.1.1:*:*:*:*:*:*:*

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