CVE-2025-50675

CVE-2025-50675 is a high-severity vulnerability with a CVSS 3.x base score of 7.8. It is not currently listed as actively exploited by CISA, and its EPSS exploit-prediction score is low. The underlying weakness is classified as CWE-732.

Key facts

Description

GPMAW 14, a bioinformatics software, has a critical vulnerability related to insecure file permissions in its installation directory. The directory is accessible with full read, write, and execute permissions for all users, allowing unprivileged users to manipulate files within the directory, including executable files like GPMAW3.exe, Fragment.exe, and the uninstaller GPsetup64_17028.exe. An attacker with user-level access can exploit this misconfiguration by replacing or modifying the uninstaller (GPsetup64_17028.exe) with a malicious version. While the application itself runs in the user's context, the uninstaller is typically executed with administrative privileges when an administrator attempts to uninstall the software. By exploiting this flaw, an attacker could gain administrative privileges and execute arbitrary code in the context of the admin, resulting in privilege escalation.

Frequently asked questions

What is CVE-2025-50675?
GPMAW 14, a bioinformatics software, has a critical vulnerability related to insecure file permissions in its installation directory. The directory is accessible with full read, write, and execute permissions for all users, allowing unprivileged users to manipulate files within the directory, including executable files like GPMAW3.exe, Fragment.exe, and the uninstaller GPsetup64_17028.exe. An attacker with user-level access can exploit this misconfiguration by replacing or modifying the uninstaller (GPsetup64_17028.exe) with a malicious version. While the application itself runs in the user's context, the uninstaller is typically executed with administrative privileges when an administrator attempts to uninstall the software. By exploiting this flaw, an attacker could gain administrative privileges and execute arbitrary code in the context of the admin, resulting in privilege escalation.
How severe is CVE-2025-50675?
CVE-2025-50675 has a CVSS 3.x base score of 7.8, rated high severity. It is exploitable over local access with low attack complexity, requires low privileges and no user interaction. Impact on confidentiality is high, integrity high, and availability high.
Is CVE-2025-50675 being actively exploited?
It is not currently listed in CISA's KEV catalog. Its EPSS exploit-prediction score is 0% (13th percentile), an estimate of the probability of exploitation in the next 30 days.
How do I fix CVE-2025-50675?
Review the linked vendor and NVD advisories for patched versions and mitigations, then upgrade or apply the recommended workaround. Given its high severity, prioritise patching exposed systems.
Does CVE-2025-50675 have an EU (EUVD) identifier?
Yes. CVE-2025-50675 is tracked in the ENISA EU Vulnerability Database (EUVD) as EUVD-2025-23937.
When was CVE-2025-50675 published?
CVE-2025-50675 was published on 2025-08-07 and last updated on 2026-06-17.

References

Other CWE-732 (Incorrect Permission Assignment for Critical Resource) vulnerabilities

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