CVE-2025-54305
CVE-2025-54305 is a high-severity vulnerability in Thermofisher Torrent Suite Software with a CVSS 3.x base score of 7.8. It is not currently listed as actively exploited by CISA, and its EPSS exploit-prediction score is low. The underlying weakness is classified as CWE-290.
Key facts
- Severity: High (CVSS 3.x base score 7.8)
- EPSS exploit prediction: 0% (4th percentile)
- Actively exploited: Not listed in CISA KEV
- EU (EUVD) id: EUVD-2025-201178
- Weakness: CWE-290
- Affected product: Thermofisher Torrent Suite Software
- Published:
- Last modified:
Description
An issue was discovered in the Thermo Fisher Torrent Suite Django application 5.18.1. One of the middlewares included in this application, LocalhostAuthMiddleware, authenticates users as ionadmin if the REMOTE_ADDR property in request.META is set to 127.0.0.1, to 127.0.1.1, or to ::1. Any user with local access to the server may bypass authentication.
Frequently asked questions
- What is CVE-2025-54305?
- An issue was discovered in the Thermo Fisher Torrent Suite Django application 5.18.1. One of the middlewares included in this application, LocalhostAuthMiddleware, authenticates users as ionadmin if the REMOTE_ADDR property in request.META is set to 127.0.0.1, to 127.0.1.1, or to ::1. Any user with local access to the server may bypass authentication.
- How severe is CVE-2025-54305?
- CVE-2025-54305 has a CVSS 3.x base score of 7.8, rated high severity. It is exploitable over local access with low attack complexity, requires low privileges and no user interaction. Impact on confidentiality is high, integrity high, and availability high.
- Is CVE-2025-54305 being actively exploited?
- It is not currently listed in CISA's KEV catalog. Its EPSS exploit-prediction score is 0% (4th percentile), an estimate of the probability of exploitation in the next 30 days.
- What products are affected by CVE-2025-54305?
- CVE-2025-54305 affects Thermofisher Torrent Suite Software. See the affected-products list for the exact vulnerable versions.
- How do I fix CVE-2025-54305?
- Review the linked vendor and NVD advisories for patched versions and mitigations, then upgrade or apply the recommended workaround. Given its high severity, prioritise patching exposed systems.
- Does CVE-2025-54305 have an EU (EUVD) identifier?
- Yes. CVE-2025-54305 is tracked in the ENISA EU Vulnerability Database (EUVD) as EUVD-2025-201178.
- When was CVE-2025-54305 published?
- CVE-2025-54305 was published on 2025-12-04 and last updated on 2026-06-17.
References
- https://assets.thermofisher.com/TFS-Assets/LSG/manuals/MAN0026163-Torrent-Suite-5.18-UG.pdf
- https://documents.thermofisher.com/TFS-Assets/CORP/Product-Guides/Ion_OneTouch_2_and_Torrent_Suite_Software.pdf
- https://www.thermofisher.com/us/en/home/life-science/sequencing/next-generation-sequencing/ion-torrent-next-generation-sequencing-workflow/ion-torrent-next-generation-sequencing-data-analysis-workflow/ion-torrent-suite-software.html
Affected products (1)
- cpe:2.3:a:thermofisher:torrent_suite_software:5.18.1:*:*:*:*:*:*:*
More vulnerabilities in Thermofisher Torrent Suite Software
- CVE-2025-54303 — Critical (CVSS 9.8): The Thermo Fisher Torrent Suite Django application 5.18.1 has weak default credentials, which are stored as fixtures…
- CVE-2025-54307 — High (CVSS 8.8): An issue was discovered in the Thermo Fisher Torrent Suite Django application 5.18.1. The…
- CVE-2025-54306 — High (CVSS 7.2): An issue was discovered in the Thermo Fisher Torrent Suite Django application 5.18.1. A remote code execution…
All CVEs affecting Thermofisher Torrent Suite Software →
Other CWE-290 vulnerabilities
- CVE-2026-48567 — Critical (CVSS 10.0): Authentication bypass by spoofing in Azure HorizonDB allows an unauthorized attacker to elevate privileges over a…
- CVE-2026-6213 — Critical (CVSS 10.0): A vulnerability in Remote Spark SparkView before build 1122 allows an attacker to bypasses the local connection check…
- CVE-2026-39858 — Critical (CVSS 10.0): Traefik is an HTTP reverse proxy and load balancer. Prior to versions 2.11.43, 3.6.14, and 3.7.0-rc.2, there is a high…
- CVE-2025-66570 — Critical (CVSS 10.0): cpp-httplib is a C++11 single-file header-only cross platform HTTP/HTTPS library. Prior to 0.27.0, a vulnerability…
- CVE-2025-34063 — Critical (CVSS 10.0): A cryptographic authentication bypass vulnerability exists in OneLogin AD Connector prior to 6.1.5 due to the exposure…
- CVE-2023-22814 — Critical (CVSS 10.0): An authentication bypass issue via spoofing was discovered in the token-based authentication mechanism that could allow…