How severe is CVE-2025-68463?

CVE-2025-68463 has a CVSS 3.x base score of 4.9, rated medium severity. It is exploitable over network with high attack complexity, requires low privileges and no user interaction. Impact on confidentiality is low, integrity none, and availability low.

Is CVE-2025-68463 being actively exploited?

It is not currently listed in CISA's KEV catalog. Its EPSS exploit-prediction score is 0% (21st percentile), an estimate of the probability of exploitation in the next 30 days.

How do I fix CVE-2025-68463?

Review the linked vendor and NVD advisories for patched versions and mitigations, then upgrade or apply the recommended workaround.

Does CVE-2025-68463 have an EU (EUVD) identifier?

Yes. CVE-2025-68463 is tracked in the ENISA EU Vulnerability Database (EUVD) as EUVD-2025-204037.

When was CVE-2025-68463 published?

CVE-2025-68463 was published on 2025-12-18 and last updated on 2026-06-17.

CVE-2025-68463

CVE-2025-68463 is a medium-severity vulnerability with a CVSS 3.x base score of 4.9. It is not currently listed as actively exploited by CISA, and its EPSS exploit-prediction score is low. The underlying weakness is classified as CWE-611.

Key facts

Severity: Medium (CVSS 3.x base score 4.9)
EPSS exploit prediction: 0% (21st percentile)
Actively exploited: Not listed in CISA KEV
EU (EUVD) id: EUVD-2025-204037
Weakness: CWE-611
Published: 2025-12-18
Last modified: 2026-06-17

Description

Bio.Entrez in Biopython through 186 allows doctype XXE.

Frequently asked questions

What is CVE-2025-68463?: Bio.Entrez in Biopython through 186 allows doctype XXE.
How severe is CVE-2025-68463?: CVE-2025-68463 has a CVSS 3.x base score of 4.9, rated medium severity. It is exploitable over network with high attack complexity, requires low privileges and no user interaction. Impact on confidentiality is low, integrity none, and availability low.
Is CVE-2025-68463 being actively exploited?: It is not currently listed in CISA's KEV catalog. Its EPSS exploit-prediction score is 0% (21st percentile), an estimate of the probability of exploitation in the next 30 days.
How do I fix CVE-2025-68463?: Review the linked vendor and NVD advisories for patched versions and mitigations, then upgrade or apply the recommended workaround.
Does CVE-2025-68463 have an EU (EUVD) identifier?: Yes. CVE-2025-68463 is tracked in the ENISA EU Vulnerability Database (EUVD) as EUVD-2025-204037.
When was CVE-2025-68463 published?: CVE-2025-68463 was published on 2025-12-18 and last updated on 2026-06-17.

References

Other CWE-611 (Improper Restriction of XML External Entity Reference (XXE)) vulnerabilities

CVE-2022-22486 — Critical (CVSS 10.0): IBM Tivoli Workload Scheduler 9.4, 9.5, and 10.1 is vulnerable to an XML External Entity Injection (XXE) attack when…
CVE-2019-14678 — Critical (CVSS 10.0): SAS XML Mapper 9.45 has an XML External Entity (XXE) vulnerability that can be leveraged by malicious attackers in…
CVE-2015-9280 — Critical (CVSS 10.0): MailEnable before 8.60 allows XXE via an XML document in the request.aspx Options parameter.
CVE-2018-1000838 — Critical (CVSS 10.0): autopsy version <= 4.9.0 contains a XML External Entity (XXE) vulnerability in CaseMetadata XML Parser that can result…
CVE-2018-1000837 — Critical (CVSS 10.0): UML Designer version <= 8.0.0 contains a XML External Entity (XXE) vulnerability in XML parser for plugins that can…
CVE-2018-1000835 — Critical (CVSS 10.0): KeePassDX version <= 2.5.0.0beta17 contains a XML External Entity (XXE) vulnerability in kdbx file parser that can…

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