How severe is CVE-2025-12922?

CVE-2025-12922 has a CVSS 3.x base score of 6.3, rated medium severity. It is exploitable over network with low attack complexity, requires low privileges and no user interaction. Impact on confidentiality is low, integrity low, and availability low.

Is CVE-2025-12922 being actively exploited?

It is not currently listed in CISA's KEV catalog. Its EPSS exploit-prediction score is 1% (41st percentile), an estimate of the probability of exploitation in the next 30 days.

What products are affected by CVE-2025-12922?

CVE-2025-12922 primarily affects Openclinica. In total, 2 product configurations (CPEs) are listed as vulnerable; see the affected-products list for the exact versions.

How do I fix CVE-2025-12922?

Review the linked vendor and NVD advisories for patched versions and mitigations, then upgrade or apply the recommended workaround.

Does CVE-2025-12922 have an EU (EUVD) identifier?

Yes. CVE-2025-12922 is tracked in the ENISA EU Vulnerability Database (EUVD) as EUVD-2025-38724.

When was CVE-2025-12922 published?

CVE-2025-12922 was published on 2025-11-10 and last updated on 2026-06-17.

CVE-2025-12922

CVE-2025-12922 is a medium-severity vulnerability in Openclinica with a CVSS 3.x base score of 6.3. It is not currently listed as actively exploited by CISA, and its EPSS exploit-prediction score is low. The underlying weakness is classified as CWE-22.

Key facts

Severity: Medium (CVSS 3.x base score 6.3)
CVSS v2: 6.5
CVSS v4: 2.1
EPSS exploit prediction: 1% (41st percentile)
Actively exploited: Not listed in CISA KEV
EU (EUVD) id: EUVD-2025-38724
Weakness: CWE-22
Affected product: Openclinica
Published: 2025-11-10
Last modified: 2026-06-17

Description

A vulnerability was found in OpenClinica Community Edition up to 3.12.2/3.13. This affects an unknown part of the file /ImportCRFData?action=confirm of the component CRF Data Import. Performing manipulation of the argument xml_file results in path traversal. The attack can be initiated remotely. The exploit has been made public and could be used. The vendor was contacted early about this disclosure but did not respond in any way.

Frequently asked questions

What is CVE-2025-12922?: A vulnerability was found in OpenClinica Community Edition up to 3.12.2/3.13. This affects an unknown part of the file /ImportCRFData?action=confirm of the component CRF Data Import. Performing manipulation of the argument xml_file results in path traversal. The attack can be initiated remotely. The exploit has been made public and could be used. The vendor was contacted early about this disclosure but did not respond in any way.
How severe is CVE-2025-12922?: CVE-2025-12922 has a CVSS 3.x base score of 6.3, rated medium severity. It is exploitable over network with low attack complexity, requires low privileges and no user interaction. Impact on confidentiality is low, integrity low, and availability low.
Is CVE-2025-12922 being actively exploited?: It is not currently listed in CISA's KEV catalog. Its EPSS exploit-prediction score is 1% (41st percentile), an estimate of the probability of exploitation in the next 30 days.
What products are affected by CVE-2025-12922?: CVE-2025-12922 primarily affects Openclinica. In total, 2 product configurations (CPEs) are listed as vulnerable; see the affected-products list for the exact versions.
How do I fix CVE-2025-12922?: Review the linked vendor and NVD advisories for patched versions and mitigations, then upgrade or apply the recommended workaround.
Does CVE-2025-12922 have an EU (EUVD) identifier?: Yes. CVE-2025-12922 is tracked in the ENISA EU Vulnerability Database (EUVD) as EUVD-2025-38724.
When was CVE-2025-12922 published?: CVE-2025-12922 was published on 2025-11-10 and last updated on 2026-06-17.

References

Affected products (2)

cpe:2.3:a:openclinica:openclinica:3.12.2:*:*:*:community:*:*:*
cpe:2.3:a:openclinica:openclinica:3.13:*:*:*:community:*:*:*

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